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Cyclodextrin (CD) info

Cyclodextrin (CD) is a general term for a series of cyclic oligosaccharides produced by amylose under the action of cyclodextrin glucosyltransferase produced by Bacillus. Cyclodextrin molecules have a slightly conical shape. The hollow cylindrical three-dimensional annular structure. At present, the

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Insulin Complexation with Cyclodextrins Through Molecular Modeling

Currently, about 5% of the world's population is affected by diabetes. The main drug for diabetes is insulin, the active form is insulin monomer, which is an unstable molecule, because long-term storage, or high temperature, will adapt monomer insulin to alternative folds, rich in β-sheets, and has

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Methyl beta cyclodextrin including pinocyst as drug carrier

Pinus can protect mice from ischemic injury by increasing cerebral blood flow in mice. In addition, pinesin has anti-allergic properties in vitro. However, the structural characteristics of pinesin itself, such as poor water solubility and low bioavailability, limit its clinical application. Therefo

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Cyclodextrin may be used for efficient hemostasis

Platelets are the first to respond to an injury. They are instantly activated, changing from a resting disc to an active fan, and they aggregate to form platelet clots that act as primary hemostasis. Platelets therefore play a vital role in hemostasis. Platelet transfusion and blood transfusion are

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