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One of Cyclodextrin Derivatives for Methyl-beta-cyclodextrin CAS No. 128446-36-6
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One of Cyclodextrin Derivatives for Methyl-beta-cyclodextrin CAS No. 128446-36-6

Methyl beta cyclodextrin as a new medicine auxiliary materical, is mainly used to strengthen the stability of the medicine, prevent it from oxidation and decomposition, also it can increase the solubility of the medicine, reduce the toxicity of it and cover up the odor and smell from it. 

Methyl beta cyclodextrin

Product Introduction 

Methyl beta cyclodextrin as a new medicine auxiliary materical, is mainly used to strengthen the stability of the medicine, prevent it from oxidation and decomposition, also it can increase the solubility of the medicine, reduce the toxicity of it and cover up the odor and smell from it. 

 

Basic information

Product Name: Methyl Beta Cyclodextrin

CAS No. : 128446-36-6

Synonyms: Methyl-β-Cyclodextrin

Molecular Formula: C42H70-nO35 • (CH3)n

Molecular Weight: 1135 + n•(14.0)

 

Product Specification 

Methyl Beta Cyclodextrin

Test Standard

Enterprise standard

ITEMS

SPECIFICATION

Appearance

White or almost white powder;Odorless, slightly sweet;Freely

 soluble in water,soluble in methanol and ethanol.

Assay

≥98%

Specific rotation

+154°~+165°

Water solution pH

pH5.0~7.5

Light-absorbing impurities

Between 230 nm and 350 nm,the absorbance is not greater

 than 1.0; and between 350 nm and 750 nm, the absorbance is

 not greater than 0.1

Average Degree of Substitution

7.0~13.3

Loss on Drying

≤7.0%

Beta cyclodextrin

≤0.2%

Residue on Ignition

≤0.5%

Heavy Metal 

≤10ppm

Sulfate

≤0.2%

Chloride

≤0.2%

The total aerobic microbial count

≤1000cfu/g

The total combined moulds 

and yeasts count

≤100cfu/g

Escherichia coli

Absence

Packaging and storage

Preserve in well-closed containers.

 

Characteristics and applications:

Methyl-beta-cyclodextrin is one of cyclodextrin derivatives that were widely used in modern researches and applications.

Methyl-beta-cyclodextrin  can be soluble both in water and in organic solvents. In pharmaceuticals industry, it can increase solubility and bioavailability of drugs, so that the efficacy of drugs can last longer with less ingestion. It can adjust and control the drug release rate, reduce drug side-effects, and enhance the stability of drugs particularly for oil-soluble molecules.

 

In commodity chemicals and cosmetics,  can reduce microbial contamination and skin irritations, keep skin moist, mask bad odors, promote transdermal absorption of activeingredients.

Methyl-beta-cyclodextrin has a larger surface tension in common cyclodextrin derivatives.


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