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Introduction of Binzhou Zhiyuan Biotechnology Sulfobutyl Beta Cyclodextrin Sodium (SBE-β-CD)
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Introduction of Binzhou Zhiyuan Biotechnology Sulfobutyl Beta Cyclodextrin Sodium (SBE-β-CD)

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Sodium sulfobutyl beta cyclodextrin

CDE platform registration number: F20190000285

USA DMF registration number: 030167

English name: SULFOBUTYL ETHER BETA CYCLODEXTRIN SODIUM

CAS NO:182410-00-0

Molecular formula: C42H70-nO35(C4H8SO3Na)n, n is the degree of substitution

Molecular weight: 1134+158n

Level: Injection

Quality standard: USP43, enterprise internal control, EP10.0


Manufacturer: Shandong Binzhou Zhiyuan Biotechnology Co.,ltd

Packing: 10KG/bag, 20KG/barrel

Application: solubilizer, wetting agent, chelating agent (complexing agent), multivalent masking agent


SBECD 182410-00-0



Sodium sulfobutyl cyclodextrin is obtained by the substitution reaction of 1,4-butane sultone (1,4-BS) with the hydroxyl group on the 2,3,6 carbons of the β-CD glucose unit. Sulfobutabeta cyclodextrin sodium is a new type of anionic highly water-soluble cyclodextrin derivative, which can be well included with drug molecules to form non-covalent complexes, thereby improving the stability, water solubility and safety of the drug It can reduce nephrotoxicity, ease drug hemolysis, control drug release rate, and mask bad odors.

At present, it has been applied to injection medicine, oral medicine, nasal medicine, eye medicine, and has special affinity and compatibility for nitrogen-containing medicines.


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