Views:0 Author:Site Editor Publish Time: 2021-07-12 Origin:Site
CDE platform registration number: F20190000285
USA DMF registration number: 030167
English name: SULFOBUTYL ETHER BETA CYCLODEXTRIN SODIUM
Molecular formula: C42H70-nO35(C4H8SO3Na)n, n is the degree of substitution
Molecular weight: 1134+158n
Quality standard: USP43, enterprise internal control, EP10.0
Manufacturer: Shandong Binzhou Zhiyuan Biotechnology Co.,ltd
Packing: 10KG/bag, 20KG/barrel
Application: solubilizer, wetting agent, chelating agent (complexing agent), multivalent masking agent
Sodium sulfobutyl cyclodextrin is obtained by the substitution reaction of 1,4-butane sultone (1,4-BS) with the hydroxyl group on the 2,3,6 carbons of the β-CD glucose unit. Sulfobutabeta cyclodextrin sodium is a new type of anionic highly water-soluble cyclodextrin derivative, which can be well included with drug molecules to form non-covalent complexes, thereby improving the stability, water solubility and safety of the drug It can reduce nephrotoxicity, ease drug hemolysis, control drug release rate, and mask bad odors.
At present, it has been applied to injection medicine, oral medicine, nasal medicine, eye medicine, and has special affinity and compatibility for nitrogen-containing medicines.