+86-531-88916568
Hydroxyproypl Beta Cyclodextrin 128446-35-5
Home » Cyclodextrin » Pharm Grade Cyclodextrins » Hydroxyproypl Beta Cyclodextrin 128446-35-5
Share to:

Hydroxyproypl Beta Cyclodextrin 128446-35-5

Hydroxypropyl betadex occurs as a white or almost white, amorphous or crystalline powder.
Hydroxypropyl betadex is the most widely used cyclodextrin derivative, the lipophilic cavity formed by 7 glucose units. Drug solubility in water is greatly improved by complexing with it.
  • HPBCD
  • 128446-35-5

Hydroxypropyl betadex

TDS-Hydroxpropyl betadex.pdf

Abbreviation

HPBCD

CAS No:

128446-35-5

Synonym:

Hydroxypropyl-beta-cyclodextrin,Hydroxypropyl-β-cyclodextrin,(2-Hydroxypropyl)-beta-cyclodextrin

Molecular formula:

C42H70-nO35(C3H8O2)n

Standard:

USP43-NF38

Quality:

Technical grade


Characteristics 

Hydroxypropyl betadex can improve the solubility of the drug in medicine, increase the efficacy of the drug or reduce the dosage, adjust or control the release rate of the drug, reduce the side effects of the drug, and enhance the stability of the drug. Mainly used for injections, injections, etc.

Hydroxypropyl betadex can be used as selective estrogen receptor modulator for the prevention of osteoporosis.

The pharmaceutical toxicology of hydroxypropyl betadex has been reviewed, and in general, the material was found to be of low toxicity. It has been suggested that hydroxypropyl betadex may have a synergistic toxic effect with, for example, carcinogens, by increasing their solubility and thus bioavailability.


Specification

Appearance

White or almost white, amorphous or crystalline powder

Solubility

Freely soluble in water and in propylene glycol

Identification

IR:

Same absoprtion bands as USP

(2-Hydroxypropyl)-beta-cyclodextrin RS


Clarity of Solution:

Positive

Molar Substitution

0.4~1.5

Beta Cyclodextrin

≤1.5%

Propylene Glycol

≤2.5%

Total impurities (excluding beta cyclodextrin and

propylene Glycol)

 ≤1.0%

Propylene Oxide

≤1ppm

Loss on drying

≤10.0%

Clarity of Solution

1.0g/2ml

1.0g/2ml water solution is clear and transparent

Conductivity

≤200μS/cm

Bacterial Endotoxins Test

 According to preparation needs

The total aerobic microbial count

 ≤1000cfu/g

The total combined moulds and yeasts count

≤100cfu/g

 

Packaging:

Normal package: 10kg/fiber drum,20kg/fiber drum.

 

Storage:

Preserve in well-closed containers,Store at room temperature.



Product Inquiry

PRODUCT CATEGORY

QUICK LINKS

CONTACT INFORMATION

Tel: +86-531-88916568
 Mail: enquiry@cydextrin.com
​​​​​​​ Address: Boxing Economic Development Zone, Binzhou, Shandong, China.

FREE CONSULTATION

Contact us
© 2020 Shandong Binzhou Zhiyuan Biotechnology Co., Ltd. All rights reserved. Sitemap