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Sulfobutyl β cyclodextrin sodium(SBECD)
| Abbreviation: | SBECD |
| CAS No: | 182410-00-0 |
| Synonym: | Sulfobutyl ether-beta-Cyclodextrin,Sulfobutyl ether-β-Cyclodextrin, Betadex Sulfobutyl ether sodium salt |
| Molecular formula: | C42H70-nO35(C4H8O3SNa)n |
| Standard: | USP43-NF38 |
| Quality: | Injection grade |
| DMF No: | 030167 |
Characteristics & Applications：
Sulfobutyl β cyclodextrin sodium( SBECD ) is an anionic, highly water-soluble cyclodextrin derivative.
SBECD can combine well with drug molecules to form non-covalent complexes,thereby SBECD has good performance in improving the stability of drugs, water solubility and safety, and can reduce nephrotoxicity, relieve hemolysis of drug , control drug release rate, mask peculiar smell, etc.
Performance：
1. Solubility:
Neutral, positive and negative APIs can be effectively combined with SBECD, so that compounds with different solubility in the API can be increased by 10 to 25,000 times.
2. Convenient administration:
SBECD has good biocompatibility and can be administered by injection, oral, eye, nose, topical and inhalation.
3. Good safety:
Under normal circumstances, SBECDcan be quickly and completely eliminated from body after administration. In vitro experiments and in vivo acute, subacute and chronic toxicity studies provide safe data and are approved for human pharmaceutical preparations.
4. Good stability:
The interaction with SBECD can provide a beneficial protective environment for the API in its lipophilic cavity, while the hydrophilic surface provides excellent water solubility, provides solubility and stability.
Speciafication:
Please find attached TDS.
Packaging:
Normal package:10kg/fiber drum
Storage:
Preserve in well-closed containers,Store at room temperature.Protect from moisture.
Sulfobutyl β cyclodextrin sodium(SBECD)
| Abbreviation: | SBECD |
| CAS No: | 182410-00-0 |
| Synonym: | Sulfobutyl ether-beta-Cyclodextrin,Sulfobutyl ether-β-Cyclodextrin, Betadex Sulfobutyl ether sodium salt |
| Molecular formula: | C42H70-nO35(C4H8O3SNa)n |
| Standard: | USP43-NF38 |
| Quality: | Injection grade |
| DMF No: | 030167 |
Characteristics & Applications：
Sulfobutyl β cyclodextrin sodium( SBECD ) is an anionic, highly water-soluble cyclodextrin derivative.
SBECD can combine well with drug molecules to form non-covalent complexes,thereby SBECD has good performance in improving the stability of drugs, water solubility and safety, and can reduce nephrotoxicity, relieve hemolysis of drug , control drug release rate, mask peculiar smell, etc.
Performance：
1. Solubility:
Neutral, positive and negative APIs can be effectively combined with SBECD, so that compounds with different solubility in the API can be increased by 10 to 25,000 times.
2. Convenient administration:
SBECD has good biocompatibility and can be administered by injection, oral, eye, nose, topical and inhalation.
3. Good safety:
Under normal circumstances, SBECDcan be quickly and completely eliminated from body after administration. In vitro experiments and in vivo acute, subacute and chronic toxicity studies provide safe data and are approved for human pharmaceutical preparations.
4. Good stability:
The interaction with SBECD can provide a beneficial protective environment for the API in its lipophilic cavity, while the hydrophilic surface provides excellent water solubility, provides solubility and stability.
Speciafication:
Please find attached TDS.
Packaging:
Normal package:10kg/fiber drum
Storage:
Preserve in well-closed containers,Store at room temperature.Protect from moisture.
