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CAS 182410-00-0 Sulfobutyl Ether-beta-Cyclodextrin
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CAS 182410-00-0 Sulfobutyl Ether-beta-Cyclodextrin

Sulfobutyl Ether-beta-Cyclodextrin Sodium is a new kind of anionic high water-soluble cyclodextrin derivative.
  • SBECD
  • 182410-00-0

Sulfobutyl Ether-beta-Cyclodextrin Sodium        

TDS-Sulfobutyl Ether-beta-Cyclodextrin Sodium.pdf


Abbreviation

SBECD

CAS No:

182410-00-0

Synonym:

Sulfobutylether-beta-Cyclodextrin,Sulfobutylether-β-Cyclodextrin,Betadex Sulfobutyl Ether Sodium salt

Molecular formula:

C42H70-nO35(C4H8O3SNa)n

Standard:

USP43-NF38

Quality:

Injection grade

DMF No:

030167


Characteristics & Applications:

Sulfobutyl Ether-beta-Cyclodextrin Sodium can be well combined with drug molecules to form non covalent complex, to play a role of improving water solubility stability,reducing nephrotoxicity,controlling drug release rate, enhancing safety of the drug, covering up bad smell, easing drug hemolysis,etc.

At present, it shows suitable performance for injection, oral administration, nasal administration and eye administration. It has special affinity and compatibility for nitrogenous drugs.


1. Solubilization:

The neutral, positive and negative APIs can effectively combine with Sulfobutyl Ether-beta-Cyclodextrin Sodium, which can increase the solubility of different compounds by 10 to 25000 times.


2. Convenient to give medicine

Sulfobutyl Ether-beta-Cyclodextrin Sodium, has good biocompatibility and can be administered by injection, oral administration, eye, nose, external use and inhalation.


3. Good security

In general, Sulfobutyl Ether-beta-Cyclodextrin Sodium can be quickly and completely eliminated from the kidney after administration. In vitro experiments and in vivo acute, subacute and chronic toxicity studies provide safe data and are approved for human drug preparations.


4. Good stability

The interaction with Sulfobutyl Ether-beta-Cyclodextrin Sodium provides a beneficial protective environment for the API in its lipophilic chamber, while the hydrophilic surface provides excellent water solubility providing solubility and stability.


Speciafication

Please find attached TDS.


Packaging:

Normal package:10kg/fiber drum,20kg/fiber drum


Storage:

Preserve in well-closed containers,Store at room temperature.Protect from moisture.

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