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Abbreviation | GCD |
CAS No: | 17465-86-0 |
Synonym: | γ-cyclodextrin |
Molecular formula: | C48H80O40 |
Quality: | Pharm grade |
Gamma-cyclodextrin is a cydextrin with 8 glucose units connected via α-1.4 sugar bonds to form a ring structure.
Gamma-cyclodextrin has a larger cavity than beta-cyclodextrin, so the cavity can contain a wider range of guest molecules; It has better water solubility, at room temperature 25℃ /100ml, the solubility of gamma-cyclodextrin is 25.6g, while the solubility of alpha-cyclodextrin is 12.7g/100ml water, and the solubility of beta-cyclodextrin is only 1.88g/100ml water.
Appearance: | White or almost white amorphous or crystalline powder . | |
Solubility: | Freely soluble in water and in propylene glycol;Very slightly soluble in alcohol. | |
Identification: | IR | Same absorption bands as USP Gamma Cyclodextrin RS |
HPLC | The retention time of the major peak of same solution corresponds to the standard solution. | |
Optical rotation | +174°~+180° | |
Assay | 98.0%~102.0% | |
Residue on lgnition | ≤0.1% | |
PH | PH 5.0~8.0 | |
Reducing Substances | ≤0.5% | |
Alpha cyclodextrin | ≤0.5% | |
Beta cyclodextrin | ≤0.5% | |
Sum of other impurities | ≤0.5% | |
Loss on Drying | ≤11.0% | |
Color and Clarity of solution | At 420nm,the absorbance is not greater than 0.2.,and the solution is clear. | |
The total aerobic microbial count | ≤1000cfu/g | |
The total combined moulds and yeasts count | ≤100cfu/g | |
Storage | Preserve in well-closed containers.Store at room temperature. | |
Normal package:20kg/fiber drum.
Abbreviation | GCD |
CAS No: | 17465-86-0 |
Synonym: | γ-cyclodextrin |
Molecular formula: | C48H80O40 |
Quality: | Pharm grade |
Gamma-cyclodextrin is a cydextrin with 8 glucose units connected via α-1.4 sugar bonds to form a ring structure.
Gamma-cyclodextrin has a larger cavity than beta-cyclodextrin, so the cavity can contain a wider range of guest molecules; It has better water solubility, at room temperature 25℃ /100ml, the solubility of gamma-cyclodextrin is 25.6g, while the solubility of alpha-cyclodextrin is 12.7g/100ml water, and the solubility of beta-cyclodextrin is only 1.88g/100ml water.
Appearance: | White or almost white amorphous or crystalline powder . | |
Solubility: | Freely soluble in water and in propylene glycol;Very slightly soluble in alcohol. | |
Identification: | IR | Same absorption bands as USP Gamma Cyclodextrin RS |
HPLC | The retention time of the major peak of same solution corresponds to the standard solution. | |
Optical rotation | +174°~+180° | |
Assay | 98.0%~102.0% | |
Residue on lgnition | ≤0.1% | |
PH | PH 5.0~8.0 | |
Reducing Substances | ≤0.5% | |
Alpha cyclodextrin | ≤0.5% | |
Beta cyclodextrin | ≤0.5% | |
Sum of other impurities | ≤0.5% | |
Loss on Drying | ≤11.0% | |
Color and Clarity of solution | At 420nm,the absorbance is not greater than 0.2.,and the solution is clear. | |
The total aerobic microbial count | ≤1000cfu/g | |
The total combined moulds and yeasts count | ≤100cfu/g | |
Storage | Preserve in well-closed containers.Store at room temperature. | |
Normal package:20kg/fiber drum.
