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2-Hydroxypropyl-β-cyclodextrin
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2-Hydroxypropyl-β-cyclodextrin

2-Hydroxypropyl-β-cyclodextrin is a derivative formed by hydroxypropyl substitution at the C2, C3 and C8 positions of beta-cyclodextrin.
  • HPBCD
  • 128446-35-5

2-Hydroxypropyl-β-cyclodextrin                                  TDS-(2-Hydroxypropyl)-beta-cyclodextrin.pdf

Abbreviation

HPBCD

CAS No:

128446-35-5

Synonym:

Hydroxypropyl-beta-cyclodextrin,Hydroxypropyl-β-cyclodextrin,(2-Hydroxypropyl)-beta-cyclodextrin

Molecular formula:

C42H70-nO35(C3H8O2)n

Standard:

Enterprise standard

Quality:

Technical grade


Characteristics:

After the hydroxyl group in beta-cyclodextrin (β-CD) is replaced by propyl group, the generated 2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) is not reductive except for the molecule, it is stable in alkaline medium, can be decomposed by strong acid, has molecular enveloping effect and is non-toxic to humans, etc. In addition to being the same as β-CD, it also has the following characteristics that are different from β-CD. E.g:

2-Hydroxypropyl-β-cyclodextrin has high water solubility at room temperature, generally exceeding 50%, so it cannot crystallize in alcohol aqueous solution.

2-Hydroxypropyl-β-cyclodextrin have different selectivity to the enveloped substances, and the ratio of molecules enveloped by some substances may change.

2-Hydroxypropyl-β-cyclodextrin is basically not catabolized or accumulated in the human body. Oral HP─β─CD is mostly excreted in the stool, and parenteral administration is basically all excreted in the urine. 

2-Hydroxypropyl-β-cyclodextrin  can promote the rapid release of enveloped substances in the body.

2-Hydroxypropyl-β-cyclodextrin  has lower surface activity and lower hemolytic activity than β─CD or other derivatives (such as methylation─β─CD), making it safer to use.


Speciafication:

Please find attached TDS.

 

Package:

Normal package:10kg/fiber drum

 

Storage:

Preserve in well-closed containers,Store at room temperature.


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